Blar i NTNU Open på forfatter "Dias, Rita de Sousa"
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Cerebral Hemodynamics in Normal Neonates During Tilt: Computer Modelling and Experiments
Jarmund, Anders Hagen (Master thesis, 2019)Nyfødte barn er sårbare for å få forstyrret blodstrømmen i hjernen. I verste fall kan forstyrrelsen føre til hjerneskader og ende med død eller livsvarige funksjonsnedsettelser. Et ultralyd-system kalt NeoDoppler har nylig ... -
Characterization of cerium oxide nanoparticles and their toxicity in Caenorhabditis elegans
Olsson, Ragni Maria Skjervold (Master thesis, 2019)Målet med denne oppgaven var å undersøke toksisiteten av CeO2 nanopartikler i modellorganismen C. elegans, og å undersøke de toksiske mekanismene for en slik effekt. Selv om CeO2 nanopartikler brukes i en rekke kommersielle ... -
Direct Determination of Chitosan–Mucin Interactions Using a Single-Molecule Strategy: Comparison to Alginate–Mucin Interactions
Haugstad, Kristin Elisabeth; Håti, Armend Gazmeno; Nordgård, Catherine Taylor; Adl, Patricia S.; Maurstad, Gjertrud; Sletmoen, Marit; Draget, Kurt Ingar; Dias, Rita de Sousa; Stokke, Bjørn Torger (Journal article; Peer reviewed, 2015)Aqueous chitosan possesses attractive interaction capacities with various molecular groups that can be involved in hydrogen bonds and electrostatic and hydrophobic interactions. In the present paper, we report on the direct ... -
DNA compaction induced by a cationic polymer or surfactant impact gene expression and DNA degradation
Ainalem, Marie-Louise; Bartles, Andrew; Muck, Joscha; Dias, Rita de Sousa; Carnerup, Anna M.; Zink, Daniele; Nylander, Tommy (Journal article; Peer reviewed, 2014)There is an increasing interest in achieving gene regulation in biotechnological and biomedical applications by using synthetic DNA-binding agents. Most studies have so far focused on synthetic sequence-specific DNA-binding ... -
Impact of overall charge and charge distribution in disordered regions on the binding between DNA and DNA-binding molecules containing disordered regions
Mardal, Ingrid (Master thesis, 2021)Samspillet mellom DNA-bindende proteiner og DNA er svært viktig i mange cellulære prosesser. Inntil nylig har det vært antatt at proteiners funksjon er direkte avhengig av deres veldefinerte, tredimensjonale struktur. ... -
In vitro studies of DNA condensation by bridging protein in a crowding environment
Ramisetty, Sravani Keerthi; Langlete, Petter; Lale, Rahmi; Dias, Rita de Sousa (Journal article; Peer reviewed, 2017)The macromolecules of the bacterial cell occupy 20–40% of the total cytosol volume, and crowded environments have long been known to compact and stabilize DNA. Nevertheless, investigations on DNA-protein binding are generally ... -
Monte Carlo Simulation and in vitro Studies on the Effects of Polysaccharide Conjugation on Enzyme Immobilization
Kelly, Michael Robert (Master thesis, 2021)I dette arbeidet ble adsorberingsevnen til konjugater av lysozym og dekstransulfat, produsert ved hjelp av Maillardreaksjonen, undersøkt. I tillegg undersøkte man grad av konjugering og enzymaktiviteten til kompleksene. ... -
Monte Carlo simulations and in vitro studies on the effect of crowder molecules on DNA condensation induced by CTAB
Killingberg, Maria (Master thesis, 2020)Prokaryote celler mangler en nukleær membran som skiller DNA-et fra cytosol, men DNA-et er pakket til en struktur kalt nukleoiden. Bindingen av nukleoidassosierte proteiner og makromolekylær trengsel, som er forårsaket av ... -
Monte Carlo Simulations of Complexation between Annealed/Quenched Polyelectrolytes and an Annealed/Quenched Nanoparticle
Kampesveen, Glenn Hoel (Master thesis, 2022)I denne studien har vi sett på hvordan systemer med 1 nanopartikkel og 1-6 polyelektrolytter påvrkes av ladningsendringer. Egenskaper som antall adsorberte polyelektrolytter, kontaktprofiler, ulike representasjoner av ... -
Monte Carlo Simulations of Complexation between Weak Polyelectrolytes and a Charged Nanoparticle. Influence of Polyelectrolyte Chain Length and Concentration
Stornes, Morten; Linse, Per; Dias, Rita de Sousa (Journal article; Peer reviewed, 2017)Complexation between multiple weak polyacid chains and a positively charged spherical nanoparticle has been studied by means of Monte Carlo simulations. By considering titration curves, it is found that variations in the ... -
Nanoparticle-Mediated Wound Closure of Human Skin
Dannert, Corinna (Master thesis, 2018)Nye studier tyder på at nanopartikler kan brukes til å lukke sår. Denne metoden kan muligens være både rask og enkel, og lukkede sår kan åpnes og justeres igjen. For at dette skal være mulig må nanopartiklene ha en sterk ... -
pH-dependent complexation of polyelectrolytes and spherical nanoparticles
Stornes, Morten (Doctoral theses at NTNU;2019:270, Doctoral thesis, 2019)The adsorption and desorption of polyelectrolytes (PEs) on other macromolecules are utilized in a number of different industries and biological applications. Electrostatic interactions are important in these systems, and ... -
pH-Dependent Polyelectrolyte Bridging of Charged Nanoparticles
Stornes, Morten; Shrestha, Binamra; Dias, Rita de Sousa (Journal article; Peer reviewed, 2018)Systems comprised of polyelectrolytes and charged nanoparticles are of great technological interest, being common components in formulations among other uses. The colloidal stability of formulations is an important issue, ... -
Spatiotemporal mapping of cascading processes in oligonucleotide-functionalized responsive hydrogels
Jonášová, Eleonóra Parelius (Doctoral theses at NTNU;2020:102, Doctoral thesis, 2020)Hydrogels – crosslinked polymer networks holding a large amount of water – have many properties that make them useful for medical applications, such as their resemblance to biological tissues, biocompatibility and ...